A home herbal remedy, rue oil is used for various gastrointestinal, cardiovascular, and other body system ailments. Known for its strong, bitter aroma, rue is a toxic yet effective insect repellent. The essential oil, also used in recipes and cosmetics, has a rich history of folklore and superstitious use.

Rue oil, also known as ruta graveolens, garden rue, or herbygrass, is used in perfume oils and other cosmetics. Herbal vinegars, alcohols, and other flavorings are sometimes made from rue. Rue oil is considered an appropriate complement to other herbs, such as wormwood, , , chamomile, vervain, royal, , and bay.