Product Name:Albendazole
Albendazole, marketed as Albenza, Eskazole, and Zentel, is a member of the compounds used as a indicated for the of a variety of infestations. Although this use is widespread in the , the (FDA) has not approved albendazole for this indication. It is marketed by .

As a vermicidal, albendazole causes degenerative alterations in the and intestinal cells of the worm by binding to the -sensitive site of , thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their stores. Degenerative changes in the , the of the germinal layer, and the subsequent release of result in decreased production of (ATP), which is the energy required for the survival of the . Due to diminished energy production, the parasite is immobilized and eventually dies.

Albendazole also has been shown to inhibit the enzyme , which is helminth-specific. This action may be considered secondary to the effect on the microtubules due to the decreased absorption of glucose. This action occurs in the presence of reduced amounts of nicotinamide-adenine dinucleotide in reduced form (NADH), which is a involved in many cellular oxidation-reduction reactions.

Albendazole has larvicidal effects in and ovicidal effects in , , and .