| Name:10-Hydroxycamptothecin;
CAS:67656-30-8;
Assay(Purity) or Standard:98%
Synonyms:4-Ethyl-4,10-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;
Molecular Formula:C20H16N2O5;
Molecular Weight:364.35;
Molecular Formula C20H16N2O5
Molecular Weight： 364.35
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Item
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Specification
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Result
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Method
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Basic Product Information
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Genus and Species
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Fructus Camptothecae Acuminatae
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Conform
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/
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Part of the Plant
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Seeds
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Conform
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/
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Country of Origin
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China
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Conform
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/
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Marker Compounds
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10-hydroxycamptothecin
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>98.0%
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99.26%
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HPLC
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Identification
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Examine by IR, consistent with the chemical reference substance.
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Complies
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Organoleptic Data
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Appearance
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Powder
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Conform
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NLS-QCS-1008
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Color
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Yellow fine powder
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Conform
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GB/T 5492-2008
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Odor
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Characteristic
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Conform
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GB/T 5492-2008
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Taste
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Characteristic
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Conform
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GB/T 5492-2008
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Process Data
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Method of Processing
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Extraction
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Conform
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/
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Solvent(s) Used
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Ethanol & Water
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Conform
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/
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Drying Method
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Vacuum drying
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Conform
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/
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Excipient
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None
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Conform
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/
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Physical Characteristics
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Melting point
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268~270°C
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269.6°C
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GB21781-2008T
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Solubility
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Soluble in DMSO, insoluble in water; slightly soluble in methanol
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Conform
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Visual
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Particle Size (80 mesh)
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98.0%pass 80mesh
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Conform
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GB/T 5507-2008
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Moisture
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<2.0%
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0.36%
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GB/T 14769-1993
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Ash Content
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<1.0%
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0.3%
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AOAC 942.05, 18th
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Solvent Residue
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Acetic acid<100ppm,
Ethanol<100ppm
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Conform
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NLS-QCS-1007
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Heavy Metals
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Total Heavy Metals
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<10 ppm
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Conform
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USP <231>, method II
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Arsenic
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<1.0 ppm
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Conform
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AOAC 986.15, 18th
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Lead
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<1.0 ppm
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Conform
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AOAC 986.15, 18th
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Mercury
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<0.5 ppm
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Conform
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AOAC 971.21, 18th
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Pesticide Residue
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666
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<0.2ppm
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Conform
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GB/T5009.19-1996
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DDT
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<0.2ppm
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Conform
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GB/T5009.19-1996
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Microbiology
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Total Plate Count
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<1,000cfu/g
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65cfu/g
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AOAC 990.12, 18th
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Total Yeast & Mold
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<100cfu/g
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12cfu/g
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FDA (BAM) Chapter 18, 8th Ed.
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E. Coli
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Negative
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Negative
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AOAC 997.11, 18th
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Salmonella
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Negative
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Negative
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FDA (BAM) Chapter 5, 8th Ed.
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Packing：25kg/drum
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