Sales Manager in Charges of The Product;
Angela Zhu
Email:chem1@top-pharmchem.com;
Sales Manager
TOP Pharm Chemical
Beta alanine
β-Alanine (or beta-alanine) is a naturally occurring beta amino acid, which is an amino acid in which the amino group is at the β-position from the carboxylate group. The IUPAC name for β-alanine is 3-aminopropanoic acid. Unlike its counterpart α-alanine, β-alanine has no stereocenter.
β-Alanine is not used in the biosynthesis of any major proteins or enzymes. It is formed in vivo by the degradation of dihydrouracil and carnosine. It is a component of the naturally occurring peptides carnosine and anserine and also of pantothenic acid (vitamin B5), which itself is a component of coenzyme A. Under normal conditions, β-alanine is metabolized into acetic acid.
β-Alanine is the rate-limiting precursor of carnosine, which is to say carnosine levels are limited by the amount of available β-alanine, not histidine.Supplementation with β-alanine has been shown to increase the concentration of carnosine in muscles, decrease fatigue in athletes and increase total muscular work done.Simply supplementing with carnosine is not as effective as supplementing with β-alanine alone since carnosine, when taken by mouth, is simply broken down during digestion to its components, histidine and beta-alanine. This results in only about 40% of the total dose being available as beta-alanine.
Reference Specification
Tests
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Limits
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Test results
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Description
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White crystals or
crystalline powder
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Crystalline powder
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Identification(IR)
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Concordant with the reference spectrum
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Concordant with the
reference spectrum
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Assay
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98.0%~ 101.0%
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99.02%
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PH
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6.5~7.5
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6.75
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State of solution
(Transmittance T430)
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≥98.0%
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97.6%
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Chloride(Cl)
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≤0.02%
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<0.02%
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Ammonium(NH4)
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≤0.02%
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<0.02%
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Sulfate(SO4)
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≤0.02%
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<0.02%
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Iron(Fe)
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≤30ppm
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<30ppm
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Heavy metals(Pb)
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≤10ppm
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<10ppm
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Arsenic(As)
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≤2ppm
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<2ppm
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Loss on drying
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≤0.30%
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0.23%
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Residue on ignition
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≤0.20%
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0.08%
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Melting point
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197~202°C
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198.5~200.0°C
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Conclusion: Passed test according to the Standard of AJI92
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